High intensity statin list1/2/2024 ![]() 6 This would help to counteract problematic polypharmacy where there has been inappropriate prescribing or where the intended benefits of medicines are not realised.Īccording to NICE NG5, 4 the key priorities for implementation relate to the following topics: 4,5 As LTCs account for around one half of all GP appointments there is an increased need to ensure appropriate polypharmacy where medicine use has been optimised. In 2012, 15 million people in England had a longterm condition (LTC), with one half of the population over the age of 60 having a LTC. NICE Guideline (NG) 5 on Medicines optimisation: the safe and effective use of medicines to enable the best possible outcomes was published in March 2015 4 (a summary of the guideline can be found on the Guidelines website). NICE article. Reproduced with permission. Medicines management options for local implementation-integrated process statement. potential opportunity to prevent the development of illness or complications, including by reducing service utilisation (for example, admissions).large variations in clinical practice with data demonstrating under usage or over usage.Therapeutic topic with a potential opportunity for improving quality, innovation, productivity or prevention because of: It should also be substantiated by an explicit and appropriate source of evidence.īox 1: Identification, prioritisation, and selection criteria for key therapeutic topics 2 The content of each topic should be fair, balanced, and accurately reflect the evidence reviewed. 2 Based on these criteria, the Department of Health's QIPP Wider Reference Group (WRG) prioritises KTTs and, after considering feedback, the final list of topics is produced by the NICE Medicines and Prescribing Centre and confirmed by the NICE executive. Box 1 (see below) highlights the identification, prioritisation, and selection criteria for KTTs. Key therapeutic topics are targeted at clinicians and local medicines optimisation services across all areas of the NHS. How are key therapeutic topics developed? Not every KTT has a comparator because currently available prescribing data may not be available to provide meaningful comparisons. The Government's white paper entitled 'Equity and excellence: liberating the NHS' 3 outlined its commitment to ensure that QIPP supports the NHS to make efficiency savings for reinvestment into the service with the aim of continually improving the quality of care. 2 The Health and Social Care Information Centre (HSCIC) leads on, and is responsible for, the development of QIPP comparators for these KTTs. Quality Innovation Productivity and Prevention (QIPP) is described as a large scale transformational programme for the NHS with national work streams designed to support the achievement of a number of quality and productivity challenges. The topics are therapeutic areas where there are potential opportunities for maintaining or improving quality and value so that resources can be released from one area of healthcare for use elsewhere. Their aim is to support the implementation of NICE guidance, either directly or by signposting the NHS to therapeutic evidence or prescribing practice relevant to existing practice. Key therapeutic topics are developed to support medicines optimisation but are only published after a consultation process and feedback from the NHS and partner organisations. The 14 topics from the January 2013 publication have been retained and updated on the basis of recently published new evidence and guidance. 1 This document was produced by the Medicines and Prescribing Centre at NICE (part of its Centre for Clinical Practice) and although the KTTs may reflect evidence-based guidance from NICE, they are not formal NICE guidance. The most recent list of key therapeutic topics (KTTs), entitled 'Medicines management options for local implementation' (see Table 1, below), was published by NICE on 15 January 2015. Menarini Farmaceutica Internazionale SRL Resource Hub
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